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LingakuLingakuどうにも + [verb（ない form）] どうにも + [i-adj 〜い → 〜くない]
Most common:
The pattern どうにも～ない expresses the idea that no matter what one does or how hard one tries, something cannot be done or changed. It conveys a strong sense of helplessness, frustration, or resignation – the situation is completely beyond one's control or ability.
どうにも literally means "by any means" or "in any way," and when combined with a negative verb or adjective, it creates the meaning "cannot … no matter what."
The most frequent combination is どうにもならない (from なる), meaning "nothing can be done about it" or "it's hopeless." This is an extremely common fixed expression.
Other verbs common include できない, とめられない止められない, うごけない動けない, etc.
This pattern is stronger than simply saying 〜～できない. It emphasizes that every possible means has been exhausted or that the speaker feels utterly powerless. It often carries an emotional tone of frustration, despair, or acceptance of an unchangeable reality.