どうにも + [verb ない-form] どうにも + [i-adj 〜い → 〜く] + ない
どうにも~ない means "can't, however hard you try". どうにも goes in front of a verb in the ない-form, usually a potential, and says every way has been tried and none worked.
The negative is what carries the meaning, so the verb has to be in the ない-form.
With なる, the pattern is the fixed phrase "nothing can be done about it". Its partner with する is どうにもできない, "I can't do anything about it". Both are everyday speech.