[sentence A]。それなのに、[sentence B]。
Sentence-initial conjunction linking two sentences where B contradicts the expectation set by A. Often expresses surprise, frustration, or disappointment.
それなのに is a conjunction meaning "and yet," "despite that," "but even so." It is used at the beginning of a sentence to express surprise, frustration, or disappointment that the result contradicts what was expected based on the previous statement. It connects two sentences where the second outcome is contrary to what the first sentence would logically lead you to expect.
それなのに is composed of それ (that) + なのに (despite/even though), and functions as a sentence-level conjunction – it refers back to the entire preceding sentence or context.
While なのに connects two clauses within a single sentence, それなのに connects two separate sentences, with それ referring back to the content of the first. This makes それなのに feel more emphatic and dramatic.
それなのに typically carries a negative emotional tone – the speaker feels that the outcome is unfair, unexpected, or frustrating. It is used when complaining, expressing regret, or highlighting an ironic contrast.
それなのに can be used in both spoken and written Japanese. In more formal writing, それにもかかわらず may be preferred.