はどうであれ is a formal expression meaning "no matter what… is like", "regardless of…", or "whatever… may be". It is used to acknowledge that a particular factor exists but to assert that it does not affect the speaker's conclusion, decision, or the main point of the statement.
The structure is: Noun + はどうであれ, where the noun represents the variable or uncertain factor being dismissed as irrelevant.
The clause following はどうであれ typically expresses a firm stance, principle, or decision that holds true irrespective of the factor mentioned. This gives the expression a tone of resolve or conviction.
This is a formal, written-style expression commonly found in essays, speeches, news commentary, and formal conversation. It carries a decisive, somewhat authoritative tone. In casual speech, speakers would more likely use どうでも or a simpler construction like 〜~にかかわらず.
This pattern frequently pairs with abstract nouns such as けっか結果 (result), りゆう理由 (reason), じじょう事情 (circumstances), かこ過去 (past), かたち形 (form/shape), ないよう内容 (content), and ほうほう方法 (method).