Refers to the hard, structural tissue that makes up the skeleton of vertebrates. It can also be used metaphorically to refer to physical strength or health.

Refers to the structure or skeleton that gives support to something, often used in both a literal and metaphorical sense.

Refers to the essential or underlying structure of something. This meaning is often used in contexts such as plans or concepts.

Refers to the metaphorical strength or resolve one possesses to face challenges or difficulties.

Describes something that requires significant effort, often implying that it is tedious or challenging.