This meaning refers to the act of holding someone responsible for a mistake or wrongdoing, often involving disapproval or dissatisfaction with their actions.

In this context, it implies confronting someone to clarify their actions or to seek truth, especially used in legal or investigative scenarios.

This meaning relates to making a situation worse, especially concerning physical conditions or feelings, often implying an increase in severity.

This meaning conveys the idea of feeling guilty or having a sense of moral or ethical discomfort about a situation, often accompanied by self-reproach.